Fig. 2
From: Transmural cellular heterogeneity in myocardial electromechanics
Schematic links between mechanisms of electromechanical coupling and mechano-calcium-electric feedback in the EO model. Solid lines show direct links between the mechanisms of excitation–contraction coupling and dashed lines show feedback links. Cooperative mechanisms of calcium activation of myofilament RUs (Xb–CaTnC, CaTnC–CaTnC and RU end-to-end cooperativity) are described in the text