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Table 3 The effect of exercise on purine nucleotide concentrations (ATP, ADP, AMP, IMP), TAN and AEC in red blood cells

From: Comparison of human erythrocyte purine nucleotide metabolism and blood purine and pyrimidine degradation product concentrations before and after acute exercise in trained and sedentary subjects

Adenine nucleotides

Sedentary group

Trained group

Rest

Post-exercise

30-min recovery

Rest

Post-exercise

30-min recovery

ATP (µmol/L RBC)

1729 (1622–1741)

1746 (1794–1969)

1781 (1791–1989)

1875 (1862–1921)*

1883 (1794–1969)*

1879 (1791–1989)*

ADP (µmol/L RBC)

240 (238–250)

245 (237–250)

221 (217–231)#

220 (205–242)

218 (207–274)

199 (169–216)#

AMP (µmol/L RBC)

22.7 (18.45–24.82)

19.6 (16.98–22.54)

12.1 (12.37–17.68)#

20.6 (16.44–25.65)

18.3 (14.58–21.50)

9.8 (7.84–9.50)#

IMP (µmol/L RBC)

7.2 (7.40–9.82)

10.9 (8.28–11.04)§

7.9 (7.17–8.58)

7.9 (7.45–10.82)

11.6 (9.98–12.54)§

8.2 (7.37–9.68)

TAN (µmol/L RBC)

1991 (1892–2150)

2010 (1912–2025)

2014 (1814–2038)

2115 (2064–2126)

2119 (2021–2157)

2088 (2002–2150)

AEC

0.93 (0.93–0.94)

0.93 (0.93–0.94)

0.95 (0.94–0.95)#

0.94 (0.94–0.95)*

0.94 (0.94–0.95)*

0.95 (0.94–0.96)#

  1. Values are given as medians (Q 25–Q 75)
  2. ATP adenosine 5′-triphosphate, ADP adenosine 5′-diphosphate, AMP adenosine 5′-monophosphate, IMP inosine 5'-triphosphate, TAN total adenine nucleotide pool, AEC adenylate energy charge
  3. * P < 0.01 different from sedentary subjects
  4. # P < 0.01 different from rest and after exercise
  5. § P < 0.01 different from rest and 30 min recovery