Fig. 3

Effect of LPS on circadian rhythm of Per2 in mouse ovary The quantified data of Per2 at day 1 and day 2 in ovary from mice with (b) or without (a) LPS treatment. White and black bars at the top of the figure indicate the time of lights-on and lights-off, respectively. Data are presented as mean ± SEM, n = 3–4, at each time point and analyzed by one-way ANOVA to examine diurnal variations in clock gene expression. Mean expression level of Per2 is shown during day 1 (c) and day 2 (d) in ovary from mice with or without LPS treatment. Data are presented as mean ± SEM analyzed by t test to determine any difference between control and LPS-treated mice (**P < 0.01)