Fig. 2

EPA-triggered Ca²⁺ release and influx. a [Ca²⁺] _i in bEND.3 cells was monitored in Ca²⁺-containing bath solution. The cells were challenged with DMSO (black line) or different concentrations of EPA. b [Ca²⁺] _i in bEND.3 cells was monitored in Ca²⁺-containing or Ca²⁺-free bath solution. The cells were challenged with 30 μM EPA. There is significant difference (P < 0.05) between the two groups beginning at 300 s and afterwards. c bEND.3 cells in Ca²⁺-containing bath solution were treated with 30 μM EPA and then washed. Results are mean ± SEM of 19–46 cells from 3 to 5 separate experiments