Fig. 6

Effects of lncRNA MALAT-1 interference on the tumor growth of nude mice bearing 786-O xenograft tumors. Si-MALAT1 stable transfection 786-O cell line was transplanted into nude mice and the mice were sacrificed after 30 days. a Relative expression of MALAT1 in tumor xenograft. b Morphology of tumor xenograft. c The change in tumor volume was determined every 4 days during the tumor growth. Statistical analysis was performed by a Student’s t test, and all measurement data are expressed as the mean volume of xenograft tumors ± SEM. **p < 0.01 vs. si-control