Table 2 Initial conditions (state variables of the model at rest)

V _m

Transmembrane potential

[Ca²⁺]_rel

Ca²⁺ concentration in the release compartment of sarcoplasmic reticulum

[Ca²⁺ ] _up

Ca²⁺ concentration in the uptake compartment of sarcoplasmic reticulum

[Ca²⁺]_i

Intracellular concentration of Ca²⁺

D

Activation gating variable for I _Ca,L

F

Voltage-dependent inactivation gating variable for I _Ca,L

f _Ca

Ca²⁺-dependent inactivation gating variable for I _Ca,L

H

Fast inactivation gating variables for I _Na

J

Slow inactivation gating variable for I _Na

M

Activation gating variable for I _Na

o _a

Activation gating variable for I _to

o _i

Inactivation gating variable for I _to

u _a

Activation gating variable for I _Kur

u _i

Inactivation gating variable for I _Kur

u

Activation gating variable for I _rel

v

Ca²⁺ flux-dependent inactivation gating variable for I _rel

w

Voltage-dependent inactivation gating variable for I _rel

x _r

Activation gating variable for I _Kr

x _s

Activation gating variable for I _Ks