Fig. 2
From: Computational simulations of the effects of the G229D KCNQ1 mutation on human atrial fibrillation
Meshes and the S1–S2 protocol. a Mesh of 2D tissue model. b Mesh of 3D human atrial tissue model acquired from Yonsei Severance Hospital, South Korea. c S1–S2 protocol in 2D. Red square represents the border of the S2 area. This depolarized area will propagate to only one direction since there is conduction block on the other direction (represented by black filled arrow), making a reentry wave. d S1–S2 protocol in 3D. White dashed lines represent the border, which S2 is given (this area will be forced back to its resting potential). The wave will propagate to this area, generating a reentry (color figure online)