Fig. 1
Changes in the soleus muscle weight relative to body weight of all experimental groups 7, 15, and 28 days after muscle injury. Con, normal control group; BPVC, bupivacaine-injected group; Ice, bupivacaine-injected and with icing applied group; Heat, bupivacaine-injected and with heat stress applied group. Values are means ± SEM. n = 6–8/group at each time point. #,§Significant main effect of treatment and time revealed by two-way ANOVA, respectively (p < 0.05). ¶Significant interaction between treatment and time revealed by two-way ANOVA (p < 0.05). *Significantly different from Con group at the same time point (p < 0.05). bSignificantly different from day 7 in each group (p < 0.05)