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Fig. 5 | The Journal of Physiological Sciences

Fig. 5

From: Ethyl 3,4-dihydroxybenzoate (EDHB): a prolyl hydroxylase inhibitor attenuates acute hypobaric hypoxia mediated vascular leakage in brain

Fig. 5

Effect of EDHB preconditioning on expression of NF-κB and cell adhesion molecules in brain of rats subjected to normoxia and hypoxia (9144 m, 5 h). a Western blot of NF-κB, ICAM-1, VCAM-1, P-selectin. b Bar graph representation. Bands were analyzed with densitometry using Image-J software. β-actin was used to normalize the results. C control, H hypoxia, D drug, DH drug + hypoxia. Values for the blots are the mean ± SD (n = 8/group). (C vs. H a p < 0.01, H vs. DH b p < 0.01, c p < 0.05)

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