Plethysmography measurements of respiratory function in conscious unrestrained mice

Table 4 Day-to-day reproducibility of respiratory values

Variable	Day 1	Day 2	r ²	p value
Respiratory rate	414 ± 8.36	416 ± 9.67	0.591	<0.000
Tidal vol (ml)	0.23 ± 0.01	0.25 ± 0.01	0.594	<0.000
Minute ventilation (ml/min)	97.5 ± 4.36	104 ± 5.40	0.612	0.003
Expiratory time (s)	0.115 ± 0.004	0.113 ± 0.004	0.474	0.005
Inspiratory time (s)	0.051 ± 0.001	0.051 ± 0.001	0.751	<0.000
Peak inspiratory flow (ml/s)	8.60 ± 0.31	7.76 ± 0.51	0.473	0.019
Peak expiratory flow (ml/s)	5.26 ± 0.27	5.15 ± 0.29	0.410	0.014
Time to relaxation (s)	0.066 ± 0.003	0.065 ± 0.003	0.334	0.037

Data are mean ± SEM. Reported p values relate to the r ² values demonstrating day-to-day reproducibility for each of the respiratory variables examined

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