Table 2 Model constants
From: Mechanisms of astrocytic K+ clearance and swelling under high extracellular K+ concentrations
Symbol | Value | Unit |
|---|---|---|
[Na+]out | 135 (control) | mM |
[K+]out | 3 (control) | mM |
[Cl−]out | 138 | mM |
A syn | 6750.0 | µm2 |
A main | 37,464.6 | µm2 |
A peri | 785.4 | µm2 |
Volorg | 3000 | µm3 |
R | 8.31 | J/(K mol) |
T | 310 | K |
F | 96,485 | C/mol |
\(\overline{{\mathop {I_{\text{NaK}} }\limits^{{}} }}\) | 1.8 × 10−4 | pA/µm2 |
\(\overline{{\mathop {I_{\text{NKCC}} }\limits^{{}} }}\) | 1.5 × 101 | pA ms/µm2 |
kf Full | 3.1 | 1/ms |
kb Full | 1.5 | 1/ms |
kf Empty | 37.8 | 1/ms |
kb Empty | 79.5 | 1/ms |
K Na | 8.4 × 10−2 | 1/mM |
K K | 1.2 × 10−3 | 1/mM |
K Cl | 5.7 × 10−2 | 1/mM |
\(\overline{{\mathop {I_{\text{KCC}} }\limits^{{}} }}\) | 4.4 × 10−5 | pA/µm2 |
\(\overline{{g_{\text{KIR,syn}} }}\) | 4.4 × 10−6 | pA/M1/2 µm2 mV |
\(\overline{{g_{\text{KIR,main}} }}\) | 4.4 × 10−7 | pA/M1/2 µm2 mV |
\(\overline{{g_{\text{KIR,peri}} }}\) | 4.4 × 10−5 | pA/M1/2 µm2 mV |
\(\overline{{\mathop {g_{\text{Cl,passive}} }\limits^{{}} }}\) | 9.3 × 10−7 | pA/µm2 mV |
\(\overline{{\mathop {g_{\text{water,syn}} }\limits^{{}} }}\) | 5.0 × 10−8 | µm mol/s mM J |
\(\overline{{\mathop {g_{\text{water,main}} }\limits^{{}} }}\) | 0 | µm mol/s mM J |
\(\overline{{\mathop {g_{\text{water,peri}} }\limits^{{}} }}\) | 5.0 × 10−8 | µm mol/s mM J |
\(\overline{{\mathop {{\text{K}}_{\text{tension}} }\limits^{{}} }}\) | 0.12 | mM/µm3 |