Fig. 4

The influences of sequential baroafferent denervation on the normalized relative slopes of the ΔMAP–ΔHR curves (a) and the ΔMAP–ΔRSNA curves (b) during the phenylephrine- or nitroprusside-induced intervention. The relative slopes of the baroreflex curves were calculated as a ratio to the control slope in the intact condition. The relative slopes of the ΔMAP–ΔHR and ΔMAP–ΔRSNA curves in both AoN–CSN and CSN–AoN groups were analyzed by a two-way ANOVA (denervation order × the number of denervated baroafferent nerves). When an interaction between the two factors was significant, the Dunnett post hoc test was performed. When a significant interaction between the two factors was absent and the main effect of the number of the denervated nerves was significant, a one-way ANOVA with repeated measures was performed with the Dunnett post hoc test. *Significant difference (P < 0.05) from the value in the intact condition. ^†Significant difference (P < 0.05) between the AoN–CSN and the CSN–AoN groups