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Fig. 3 | The Journal of Physiological Sciences

Fig. 3

From: A protein tyrosine kinase receptor, c-RET signaling pathway contributes to the enteric neurogenesis induced by a 5-HT4 receptor agonist at an anastomosis after transection of the gut in rodents

Fig. 3

Immunohistochemical detection of PGP 9.5-positive cells at the anastomosis in the rectum of LT with a cAMP-dependent protein kinase A (PKA) inhibitor, H89 (30 µM) + MOS (100 µM)-drinking water rat for 2 weeks after surgery (A). The average number of neurons observed at the anastomosis in the rectum at each of 2 levels of 3 rats in the MOS group (n = 6) and H89 + MOS group (n = 6) was each significantly larger than that in the DMSO group (n = 6) (*P < 0.05) for 2 weeks after surgery (B). There was no significant difference in the average number of neurons between the anastomosis in the MOS and H89 + MOS groups (B)

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