Fig. 6
From: Luminal trypsin induces enteric nerve-mediated anion secretion in the mouse cecum
Changes in I sc and G t induced by 5-HT. a Time-course characteristics for the I sc and G t changes induced by 5-HT (1 μM) added to the serosal side (n = 8). b Effects of TTX (300 nM), or the 5-HT3 and 5-HT4 receptor antagonists (20 μM bemesetron and 10 μM SB-204070, respectively) on the I sc induced by 5-HT. Each inhibitor was added to the serosal side 20 min before adding 5-HT. Values for the maximum increase in I sc (ΔI sc) induced by 5-HT were compared in the presence and absence of the inhibitors. Six animals were used for TTX, and three for the 5-HT receptor antagonists. *0.01 < P < 0.05 compared with the control response that was determined in the adjacent tissue by using the paired t test