Persistent overexpression of SERCA2a affects bladder functions under physiological conditions, but not in bladder outlet obstruction-induced sub-acute pathological conditions

Table 1 Body weights, bladder weights, VV, PVR and bladder compliance in WT, TG, WTBOO and TGBOO

	WT (n = 10)	TG (n = 10)	WTBOO (n = 5)	TGBOO (n = 5)
Body weights (g)	277 ± 33	294 ± 23	310 ± 27	324 ± 16
Bladder weights (mg)	136 ± 32	143 ± 17	486 ± 22**	507 ± 29^#
Voided volume (W) (mL)	1.41 ± 0.12	1.1 ± 0.19**	0.54 ± 0.11**	0.61 ± 0.21^#
Post void residual (PVR) (mL)	0	0	1.36 ± 0.26**	1.4 ± 0.2^#
Bladder compliance (mL/cmH₂O)	0.174 ± 0.05	0.119 ± 0.06*	0.107 ± 0.04*	0.106 ± 0.03

Values are presented as the mean ± SD
WT wild type, TG transgenic, WTBOO bladder outlet obstruction model of WT, TGBOO bladder outlet obstruction model of TG, n number of animals
* P < 0.05 vs. WT, **P < 0.001 vs. WT, ^# P < 0.001 vs. TG

ISSN: 1880-6562