Fig. 2
From: ABCG1 deficiency promotes endothelial apoptosis by endoplasmic reticulum stress-dependent pathway
Downregulation of ABCG1 promoted endothelial apoptosis. Annexin V-FITC/PI double-staining assay was used to quantify apoptosis in HUAEC by means of flow cytometry. Endothelial apoptosis includes early apoptotic (FITC +PI−) and late apoptotic (FITC +PI+). a Apoptosis in endothelial control, b increased apoptosis in ABCG1-deficient EC, c apoptosis in ABCG1-deficient EC transfected with ABCG1 plasmid, d apoptosis in endothelial control transfected with ABCG1 plasmid