| EE | Reference | LE | Reference |
---|
I
Na
| 0.07 | [3] | 1.00 | [3] |
I
CaL
| 0.46 | [22] | 0.78 | [2] |
I
K1
| 0.11 | [36] | 1.00 | [2] |
I
Kr
| 2.0 | [16, 17] | 2.0 | [2, 18] |
I
KATP
| 0.32 | [3, 37] | 0.88 | [37, 38] |
I
to
| 0.01 | [3] | 0.27 | [38] |
- The densities relative to that in the adult stage of the Na+ current (I
Na), L-type Ca2+ current (I
CaL), inward rectifier K+ current (I
K1), ATP-sensitive K+ current (I
KATP), and transient outward current (I
to) for the early embryonic (EE) and late embryonic (LE) stages were estimated from the current–voltage (I–V) curves of cells in vitro. The I–V curve for I
Na was obtained from 11- to 13-day postcoitum (dpc), and 17- to 20-dpc mice [3]. For I
CaL, the early embryonic I–V curve was obtained from 9.5-dpc mice [22]; the late embryonic I–V curve was obtained from 18-dpc mice [22] and fetal guinea pigs 1–7 days before birth [2]. For I
K1, I–V curves were obtained for the 12-dpc rat [36] and the fetal guinea pig 1–7 days before birth [2]. The relative densities of I
KATP were obtained on the basis of the data for the 12-dpc and 18-dpc rats [37]. For I
to, I–V curves were obtained for 11-dpc mice [3] and 1-day-old rats [38]