Fig.. 3From: Stage-dependent anti-allodynic effects of intrathecal Toll-like receptor 4 antagonists in a rat model of cancer induced bone painThe effects of LPS-RS on cancer-induced bone pain. I.t. administration of LPS-RS (20 μg) increased PWTs significantly at day 8 (a) and day 12 (b) after surgery while LPS-RS (10, 20, 40 μg) showed no effect at day16 (c). *P < 0.05 versus NS-treated ratsBack to article page