Fig. 7

Ratio of 150- and 145-kD proteolytic fragments by calpain to 240-kD intact α-fodrin in the time control, mI-R, and SNJ + mI-R groups. Upper panel each representative band in the time control, mI-R, and SNJ + mI-R groups. All bands were obtained from the same SDS–polyacrylamide gel. Lower panel mean fold change of 150- and 145-kD fragments to 240-kD α-fodrin compared to mean value (=1.0) in the time control (n = 9) group among the mI-R (n = 9) and SNJ + mI-R (n = 5) groups. Data show the mean with SD. *P < 0.05 versus time control, ^# P < 0.05 versus mI-R. Immunoblotting of 150- and 145-kD fragments of α-fodrin (240-kD)