Table 2 Influence of (a) physical training and (b) acute physical exercise on peroxiredoxin (PRDX) contents
From: Peroxiredoxins and sports: new insights on the antioxidative defense
Study | Training program/ physical activity | Subjects | Cells/ cellular compartments | PRDX system |
|---|---|---|---|---|
Physical training | ||||
 Moghaddam et al. [20] | 3 months, 3 times a week, cycling (25–50 min, 75 % HRmax) | Type 2 diabetic men (n = 6) | Erythrocytes | PRDX1 ↔ PRDX2 ↑ |
 Brinkmann et al. [21] | 3 months, twice a week, cycling (25–50 min, HR: corresponding to 2 mmol/l blood lactate concentration) or whole body strength training (30–75 % 1-RM) | Type 2 diabetic men (n = 16) | Skeletal muscle cells, musculus vastus lateralis | PRDX1 ↔ PRDX2 ↔ PRDX3 ↔ PRDX4 ↔ PRDX5 ↑ PRDX6 ↔ |
 Kavazis et al. [22] | 10 days, daily, treadmill running (10–60 min, 30 m/min, 0° inclination, 70 % maximal oxygen consumption) | Male Sprague–Dawley rats (n = 8) | Isolated mitochondria from heart muscle cells |  |
subsarcolemmal | PRDX3 ↑ | |||
intermyofibrillar | PRDX3 ↔ | |||
 Richters et al. [23] | 2 months, 5 times a week, treadmill running (1 h, 15 m/min, 5° inclination) | Male SOD2-knock-out-mices (n = 14) | Heart muscle cells | PRDX1 ↑ PRDX2 ↓ PRDX3 ↑ PRDX4 ↑ PRDX5 ↔ PRDX6 ↔ |
Acute physical exercise | ||||
 Brinkmann et al. [24] | WHO cycling step test to physical exhaustion (25 W + 25 W every 2 min) | Type 2 diabetic men (n = 15) | Erythrocytes | PRDX-SO2–3 ↑ |
Non-diabetic men (n = 12) |  | PRDX-SO2–3 ↔ | ||