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Table 3 Pharmacologic manipulation of VNS defibrillation success rates

From: Autonomic boundary conditions for ventricular fibrillation and their implications for a novel defibrillation technique

 

VF episodes

Defibrillation (50 Hz)

Average success % (SD)

n (rats)

Pre-drug

72

59

81 % (32)

31

L-NAME

14

13

94 % (14)

6

L-NAME and atropine

27

11

31 % (29)*

5

  1. Use of atropine alone prevented VNS defibrillation in all attempts in one animal
  2. * Indicates significantly lower than all other groups (p = 0.004)