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Table 1 Biochemical parameters at the end of the study

From: Glyoxalase 1 and glyoxalase 2 activities in blood and neuronal tissue samples from experimental animal models of obesity and type 2 diabetes mellitus

 

Wistar

Goto-Kakizaki

Zucker lean

Zucker fa/fa

Fed state

 Insulin (ng/ml)

2.15 ± 0.43

3.67 ± 0.86

1.44 ± 0.18

11.39 ± 1.31#

 Free fatty acids (mM)

0.37 ± 0.03

1.05 ± 0.13*

0.54 ± 0.03

0.91 ± 0.05#

 HbA1C (%)

7.59 ± 0.33

8.39 ± 0.14*

5.75 ± 0.37

6.74 ± 0.22#

Fasted state

 Insulin (ng/ml)

0.31 ± 0.03

0.48 ± 0.07*

0.50 ± 0.04

5.01 ± 0.75#

 Free fatty acids (mM)

1.22 ± 0.06

1.47 ± 0.08*

1.23 ± 0.07

1.28 ± 0.07

 Glucose tolerance test (AUC)

1473 ± 110

3932 ± 221*

812 ± 62

1542 ± 131#

  1. The values are presented as the mean ± SEM of at least 11 animals
  2. * p < 0.05 compared to the Wistar control
  3. # p < 0.05 compared to the Zucker lean control