Fig. 4
Endothelium-dependent relaxation of isolated aortic rings in Wistar, Goto-Kakizaki, Zucker lean and Zucker fa/fa rats. Concentration–response curve of acetylcholine (10−10–10−5M) in isolated aortic rings of Wistar and Goto-Kakizaki (a) and Zucker lean and fa/fa (b) rats at 24 weeks of age. The data are presented as the mean % of relaxation ± SEM of at least 11 animals. *p < 0.05 compared to the control group