Fig. 3

Glyoxalase 1 (Glo1) and glyoxalase 2 (Glo2) activities in neuronal tissues. Glo1 and Glo2 activity in the cortex, hypothalamus, spinal cord and sciatic nerve tissues from Wistar, Goto-Kakizaki (a, b) and Zucker fa/fa and lean (c, d) rats at 24 weeks of age. Non-diabetic rats (white bars), diabetic rats (black bars). The Glo1 activity in tissue homogenates was defined as the μmol of S-d-lactoylglutathione formed per min per g of protein. The Glo2 activity in tissue homogenates was defined as μmol of S-d-lactoylglutathione hydrolysed per min per g of protein. The data are presented as the mean ± SEM of at least 6 animals. *p < 0.05 compared to the control group