Fig. 2

Glyoxalase 1 (Glo1) and glyoxalase 2 (Glo2) activities in blood. Changes in Glo1 and Glo2 activity in blood from Wistar, Goto-Kakizaki (a, b) and Zucker fa/fa and lean (c, d) rats from 8 to 24 weeks of age. The Glo1 activity in the whole blood lysates was defined as the μmol of S-d-lactoylglutathione formed per min per g of haemoglobin. The Glo2 activity in the whole blood lysates was defined as μmol of S-d-lactoylglutathione hydrolysed per min per g of haemoglobin. The data are presented as the mean ± SEM of at least 11 animals. *p < 0.05 compared to the control group, ^# p < 0.05 compared to 8 weeks in the respective group