Fig. 1

ROS production in cancer cells and normal cells at different temperatures. a ROS production in cancer cells at 32, 37, and 42°C. Prostate cancer cells were incubated at different temperatures, followed by determination of ROS production (mean ± SEM; n = 4, *p < 0.05). b ROS production in cardiac fibroblasts at 37 and 42°C. Cardiac fibroblasts were incubated at different temperatures similarly, followed by determination of ROS production (mean ± SEM; n = 4, *p < 0.05). c ROS production was determined with cancer cells in the presence of an increasing concentration of ascorbic acid (10 μM–100 mM). Prostate cancer cells were incubated at 37°C, followed by determination of ROS production (mean ± SEM; n = 4, *p < 0.05)