Fig. 8From: Subepithelial trypsin induces enteric nerve-mediated anion secretion by activating proteinase-activated receptor 1 in the mouse cecumEffects of pretreating by SLIGRL-NH 2 , a PAR2-AP, on the trypsin-induced increase in I sc (ΔI sc). a The control ΔI sc value induced by serosal trypsin (100 nM). Mean values are presented, n = 14. b ΔI sc induced by trypsin was obtained for tissue that had been treated with serosal SLGRL-NH2. Mean values are presented, n = 7. c ΔI sc values induced by serosal trypsin are presented in the tissue that had been pre-exposed to SLGRL-NH2 or not. Each data value is presented as the mean ± SE. *P < 0.05, unpaired t testBack to article page