Fig. 1

Effects of margatoxin and chloroquine on voltage-dependent outward currents in murine thymocytes. Effects of the external solution containing no reagents (a), 100 nM margatoxin (b) and 10 µM chloroquine (c). Typical whole-cell current traces recorded before and after the reagent application, and/or after its washout. The currents were elicited from the holding potential of −80 mV to the various voltage steps as depicted in the voltage protocol. Each pulse was applied for a 200-ms duration between 10-s intervals