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Table 1 Correspondence between humoral and histological evaluations for GC and DHEA

From: T cells affect thymic involution during puberty by inducing regression of the adrenal reticularis

 

Humoral evaluation

Histological evaluation

GC (ng/ml)

DHEA (ng/ml)

GC/DHEA ratio

ZF (μm)

ZR (μm)

ZF/ZR ratio

6 weeks

131.1 ± 83.9

2.7 ± 2.4

48.0 ± 30.7

221.1 ± 21.0

87.1 ± 17.1

52.9 ± 30.6

16 weeks

89.9 ± 48.9

0.7 ± 0.7

122.0 ± 63.7

239.1 ± 21.9

37.0 ± 5.1

431.7 ± 114.6

Comparison, p value

NS

p < 0.05

p < 0.05

NS

p < 0.01

p < 0.01

  1. Serum GC and DHEA levels (ng/ml) in 6- and 16-week-old BALB/c mice were measured by ELISA assay, and GC/DHEA ratios were calculated. ZF widths for GC activity and ZR widths for DHEA activity (μm) on the paraffin sections stained with HE were histologically measured. The ZF/ZR ratios were estimated from the calculated volumes of the ZF and ZR (cf. “Materials and methods”). All data are presented as the mean ± SD of several mice (n = 4–8/group)