Fig. 2
From: T cells affect thymic involution during puberty by inducing regression of the adrenal reticularis
Delay of thymic involution by preventing the generation of peripheral T cells. Anti-CD3 antibody (5.5 μg/g of b.w.) was i.p. injected within 24 h of birth and weekly thereafter into female newborn BALB/c mice for 2 (shaded circles) or 6 weeks (closed circles) after birth, and the number of T cells in the spleen (a) and the number of thymocytes (b) at the given age are indicated. Open circles indicate control untreated group. Each symbol with a bar indicates the mean ± SD (n = 2–5). c Flow cytometric profile of thymocytes from 2 and 8-week-old mice, which were treated continually 2 and 7 times, respectively, with anti-CD3 antibodies or PBS as a control