Fig. 1
From: T cells affect thymic involution during puberty by inducing regression of the adrenal reticularis
Age-related changes in the thymi of BALB/c mice. a Number of thymocytes from female (open circles) and male (closed circles) mice of various ages plotted against age. Closed squares and triangles with a SD bar indicate the number of thymocytes in castrated and sham-operated male mice. H&E-stained sections shown are from thymi of 1- and 6-month-old female mice. Scale bars 1 mm. b Kinetic profiles of the number of CD4 or CD8 single-positive (shaded bars), CD4 and CD8 double-positive (open bars) and CD4 and CD8 double negative cells (closed bars). Flow cytometric profiles shown are representative of thymocyte subpopulations of 1-month-old (n = 8) and 6-month-old (n = 4) female mice in reference to CD4- and CD8-expressing cells