Table 1 Resting levels of MAP after gene-knockout of each hormone or receptor

Angiotensin

 Renin

~35 s ↓

Yanai et al. [7]

 Angiotensinogen

~33 s ↓

Ishida et al. [8]

 Angiotensinogen

~34 ↓

Tsuchida et al. [9]

 AT1a receptor

~24 s ↓

Ito et al. [10]

 ATla + ATlb

~34 ↓

Tsuchida et al. [9]

 AT2 receptor

~0

Hein et al. [11]

 ACE 0-copy

~32 ↓

Carlson et al. [12]

 ACE 1-copy

~14 ↓

Carlson et al. [12]

Vasopressin

Brattleboro rat

~7 ↑

Gardiner et al. [13]

Bradykinin

B2 receptor

~8 s↑

Madeddu et al. [14]

ANP

 Molecule

(~14 ↑)

John et al. [15]

 Whole-body GC-A receptor

~10 ↑

Lopez et al. [16]

 Vascular GC-A receptor

~0

Holtwick et al. [17]

Adrenomedullin

 Molecule^+/−

~11 ↑

Shindo et al. [18]

Uroguanylin

 GC-C receptor

~0

Potthast et al. [19]

EDLF

 ‘Digibind’

(~0)

Kaide et al. [20]