Fig. 1

Daily food intake (expressed by weight (a) or energy (b)) and body weight (c) of the male rats fed on ordinary chow (OC) or a high-fat diet (HFD). The food for half of the rats (n = 8) was changed from OC to the HFD on day −1; other rats (n = 8) were continued to be fed OC. Food intake increased temporally after the food change from OC to HFD, but gradually decreased to the amount which contained the same amount of calories and remained stable even after their body weight was significantly heavier than that of OC rats. Values are group mean ± SEM. *P < 0.05, **P < 001 between OC and HFD rats