Fig. 2

Effects of catecholamine on poly I:C-induced TNF-α (a–c) and IFN-β (d–f) production in RAW 264 cells. RAW264 cells (n = 8–11) were treated with epinephrine (1 μM; a, d), norepinephrine (1 μM; b, e), dopamine (1 μM; c, f), or vehicle 30 min before poly I:C (10 μg/ml) stimulation for 6 h. Results are expressed as the means ± SEM. *p < 0.05 and **p < 0.01 vs. vehicle. Statistical analysis was performed with the Student t test