Fig. 2

Effects of endothelin-1 (ET-1) (black columns) and the combined infusion of BQ-123 and ET-1 (gray columns) on blood flow in different organs presented as % change from baseline. a Normal SpD-rats and b diabetic rats (SpD-STZ). Data are the mean ± SEM. Asterisk above column shows significance at P < 0.05 regarding change in blood flow compared to baseline; asterisk on line shows significance between ET-1 and after BQ-123 administration within each group of animals