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Table 3 Characteristics of the OGTT-derived insulin secretion and insulin sensitivity indices of the subjects [25, 26]

From: Computational assessment of insulin secretion and insulin sensitivity from 2-h oral glucose tolerance tests for clinical use for type 2 diabetes

 

Subjects used in the evaluation of insulin secretion

Subjects used in the evaluation of insulin sensitivity

All

NGT

IGT

T2D

All

NGT

IGT

T2D

n

46

9

5

32

79

10

11

58

HOMA-β (mg dl−1 μU−1 ml)

89 ± 155

261 ± 292

78 ± 22

42 ± 47

72 ± 123

240 ± 283

65 ± 42

44 ± 46

HOMA-R (mg dl−1 μU ml−1)

1.82 ± 1.58

2.41 ± 2.90

1.43 ± 0.79

1.72 ± 1.12

1.69 ± 1.41

2.26 ± 2.77

1.47 ± 1.14

1.63 ± 1.11

II index (mg−1 dl μU ml−1)

0.44 ± 0.83

1.60 ± 1.36

0.32 ± 0.28

0.14 ± 0.18

0.33 ± 0.66

1.51 ± 1.32

0.26 ± 0.22

0.14 ± 0.16

Insulin0-120 (AUC) (μU ml−1)

37.0 ± 40.2

85.9 ± 63.7

41.1 ± 18.2

22.6 ± 18.6

32.2 ± 32.3

82.0 ± 61.3

34.3 ± 17.4

23.2 ± 16.3

QUICKI (arbitrary unit)

0.367 ± 0.040

0.367 ± 0.057

0.372 ± 0.036

0.366 ± 0.037

0.371 ± 0.040

0.370 ± 0.054

0.379 ± 0.044

0.369 ± 0.037

Matsuda index (mg−1 dl μU ml−1)

6.91 ± 4.58

5.88 ± 4.22

5.80 ± 1.65

7.38 ± 4.97

7.09 ± 4.16

5.92 ± 3.98

7.16 ± 3.69

7.28 ± 4.31

OGIS120 (ml min−1 m−2)

369 ± 59

422 ± 63

418 ± 45

346 ± 45

372 ± 55

424 ± 60

415 ± 40

355 ± 47

p I4 (μU ml−1 mg−1 dl min−1)

0.089 ± 0.134

0.291 ± 0.189

0.109 ± 0.049

0.029 ± 0.031

0.070 ± 0.106

0.275 ± 0.185

0.083 ± 0.047

0.032 ± 0.029

p G3 (μU−1 ml min−2 10−6)

4.95 ± 5.06

6.58 ± 6.32

6.70 ± 2.01

4.22 ± 4.95

5.13 ± 5.09

7.65 ± 5.44

3.84 ± 3.13

4.29 ± 5.01