Table 2 Aorta-dominant genes
| Â | Probe set ID | RefSeq transcript ID | Gene title | Gene symbol | Fold difference between aorta and DA | |
|---|---|---|---|---|---|---|
e19 | e21 | |||||
1 | X15939_r_at///rc_AI104924_f_at///rc_AI103920_f_at///rc_AA891522_f_at | NM_017239 | Myosin heavy chain, polypeptide 6, cardiac muscle, alpha | Myh6 | 2.2 | 23.8 |
2 | X80130cds_i_at///rc_AI104567_g_at///rc_AA866452_s_at | XM_215801 | Actin alpha cardiac 1 | Actc1 | 3.0 | 18.4 |
3 | M93638_at | NM_183333 | Keratin complex 2, basic, gene 5 | Krt2-5 | 6.9 | 16.8 |
4 | rc_AA891242_g_at///rc_AA891242_at | NM_001106017 | Myosin, light polypeptide 7, regulatory | Myl7 | 3.2 | 15.3 |
5 | X15939_f_at | NM_017240 | Myosin, heavy polypeptide 7, cardiac muscle, beta | Myh7 | 1.9 | 13.2 |
6 | D78159mRNA_s_at | NM_001008806 | Type II keratin Kb4 | Kb4 | 1.5 | 9.1 |
7 | X15512_at | NM_012824 | Apolipoprotein C–I | Apoc1 | 0.5 | 7.4 |
8 | U67914_at | XM_342219 | Carboxypeptidase A3 | Cpa3 | 1.7 | 7.2 |
9 | rc_AI169372_g_at | NM_031839 | Cytochrome P450, family 2, subfamily c, polypeptide 23 | Cyp2c23 | 0.5 | 5.5 |
10 | K01933_at | NM_012582 | Haptoglobin | Hp | 0.5 | 5.1 |
11 | M80829_at | NM_012676 | Troponin T2, cardiac | Tnnt2 | 1.3 | 4.8 |
12 | X00975_g_at///X07314cds_at | NM_001035252 | Myosin, light polypeptide 2 | Myl2 | 5.1 | 4.8 |
13 | M24852_at | NM_013002 | Purkinje cell protein 4 | Pcp4 | 4.7 | 4.8 |
14 | M92074_g_at | NM_017144 | Troponin I, cardiac | Tnni3 | 2.1 | 4.6 |
15 | rc_AA945054_s_at | NM_022245 | Cytochrome b-5 | Cyb5 | 0.8 | 4.1 |
16 | S76779_s_at | NM_138828 | Apolipoprotein E | Apoe | 1.3 | 3.9 |
17 | AF014503_at | NM_053611 | Nuclear protein 1 | Nupr1 | 3.2 | 3.9 |
18 | X02412_at | NM_019131 | Tropomyosin 1, alpha | Tpm1 | 1.0 | 3.7 |
19 | D00752_at | NM_182474 | Serine protease inhibitor | Spin2a | 0.5 | 3.6 |
20 | D89730_at | NM_001012039 | Epidermal growth factor-containing fibulin-like extracellular matrix protein 1 (predicted) | Efemp1_predicted | 4.0 | 3.6 |
21 | M14656_at | NM_012881 | Secreted phosphoprotein 1 | Spp1 | 4.7 | 3.4 |
22 | X81448cds_at///rc_AI072634_at | NM_053976 | Keratin complex 1, acidic, gene 18 | Krt1-18 | 1.5 | 3.1 |
23 | rc_AA946368_at | XM_575338 | Similar to fatty acid translocase/CD36 | LOC499984 | 1.9 | 3.1 |
24 | M91595exon_s_at///J04486_at///A09811cds_s_at | NM_013122 | Insulin-like growth factor binding protein 2 | Igfbp2 | 2.1 | 3.1 |
25 | U30938_at | NM_013066 | Microtubule-associated protein 2 | Mtap2 | 2.1 | 3.0 |
26 | Y12502cds_at | NM_021698 | Coagulation factor XIII, A1 subunit | F13a | 2.8 | 2.9 |
27 | M84719_at | NM_012792 | Flavin containing monooxygenase 1 | Fmo1 | 4.4 | 2.8 |
28 | M91652complete_seq_at | NM_017073 | Glutamine synthetase 1 | Glul | 1.8 | 2.8 |
29 | J03752_at | NM_134349 | Microsomal glutathione S-transferase 1 | Mgst1 | 1.1 | 2.7 |
30 | AF072411_g_at///rc_AA925752_at | NM_031561///XM_575338///XM_575339 | CD36 antigen///similar to fatty acid translocase/CD36///similar to fatty acid translocase/CD36 | Cd36///LOC499984///LOC499985 | 1.7 | 2.7 |
31 | L19998_g_at///L19998_at | NM_031834 | Sulfotransferase family 1A, phenol-preferring, member 1 | Sult1a1 | 2.9 | 2.7 |
32 | L25387_g_at | NM_206847 | Phosphofructokinase, platelet | Pfkp | 1.7 | 2.6 |
33 | rc_AI230247_s_at | NM_019192 | Selenoprotein P, plasma, 1 | Sepp1 | 2.2 | 2.6 |
34 | rc_AI237731_s_at///L03294_g_at///L03294_at | NM_012598 | Lipoprotein lipase | Lpl | 0.9 | 2.6 |
35 | M83680_at | NM_053589 | RAB14, member RAS oncogene family | Rab14 | 2.6 | 2.6 |
36 | rc_AI639532_at | XM_215935 | Troponin C2, fast (predicted) | Tnnc2_predicted | 4.7 | 2.5 |
37 | X71127_g_at | NM_019262 | Complement component 1, q subcomponent, beta polypeptide | C1qb | 3.2 | 2.5 |
38 | AB000113_at | NM_017217 | Solute carrier family 7 (cationic amino acid transporter, y + system), member 3 | Slc7a3 | 1.6 | 2.5 |
39 | rc_AA894092_at | XM_342245 | Periostin, osteoblast specific factor (predicted) | Postn_predicted | 2.5 | 2.5 |
40 | M32062_g_at | NM_053843///XM_573502///XM_573503 | Fc receptor, IgG, low affinity III///Fc gamma receptor II beta///similar to low affinity immunoglobulin gamma Fc region receptor III precursor (IgG Fc receptor III) (Fc-gamma RIII) (FcRIII) | Fcgr3///LOC498276///LOC498277 | 3.2 | 2.4 |
41 | M24353_g_at | XM_343636 | Mannosidase 2, alpha 1 | Man2a1 | 4.7 | 2.3 |
42 | U77931_at | NM_147136 | rRNA promoter binding protein | RGD:727924 | 3.0 | 2.3 |
43 | M12098_s_at | NM_012604 | Myosin, heavy polypeptide 3, skeletal muscle, embryonic | Myh3 | 2.7 | 2.1 |
44 | AJ005396_at | XM_342325 | Procollagen, type XI, alpha 1 | Col11a1 | 3.1 | 2.1 |
45 | rc_AA893230_at | XM_236325 | Ceroid-lipofuscinosis, neuronal 6 (predicted) | Cln6_predicted | 2.8 | 2.1 |
46 | rc_AA875172_at | NM_053360 | SH3-domain kinase binding protein 1 | Sh3kbp1 | 2.6 | 2.1 |
47 | AB012235_at///AB012234_g_at///AB012234_at | XM_213849 | Nuclear factor I/X | Nfix | 4.9 | 1.9 |
48 | X00722_at | XM_578812 | Similar to testin | LOC503278 | 2.8 | 1.9 |
49 | M32062_at | NM_053843///XM_573502 | Fc receptor, IgG, low affinity III///Fc gamma receptor II beta | Fcgr3///LOC498276 | 2.8 | 1.8 |
50 | rc_AI013472_at///rc_AA924925_at | NM_138905 | ER transmembrane protein Dri 42 | Ppap2b | 2.6 | 1.8 |
51 | U62897_at | NM_012836 | Carboxypeptidase D | Cpd | 3.0 | 1.8 |
52 | Z12298cds_s_at///X59859_r_at///X59859_i_at | NM_024129 | Decorin | Dcn | 2.7 | 1.7 |
53 | M15797_at | XM_213954 | Nidogen (entactin) | Nid | 13.4 | 1.7 |
54 | AF041066_at | NM_020082 | Ribonuclease, RNase A family 4 | Rnase4 | 2.9 | 1.7 |
55 | U50842_at | XM_343427 | Neural precursor cell expressed, developmentally downregulated gene 4A | Nedd4a | 3.9 | 1.6 |
56 | rc_AA866443_at | NM_001008560 | Protease, serine, 35 (predicted) | Prss35 | 4.2 | 1.6 |
57 | S66184_s_at///rc_AI234060_s_at///rc_AI102814_at///rc_AA875582_at | NM_017061 | Lysyl oxidase | Lox | 3.2 | 1.6 |
58 | rc_AI639314_at | XM_238213 | Delangin (predicted) | NIPBL_predicted | 2.5 | 1.6 |
59 | rc_AA800908_at | XM_344450 | Potassium channel tetramerisation domain containing 12 (predicted) | Kctd12_predicted | 3.6 | 1.6 |
60 | rc_AI029920_s_at | NM_012817 | Insulin-like growth factor binding protein 5 | Igfbp5 | 4.0 | 1.5 |
61 | L10326_at | NM_019132 | GNAS complex locus | Gnas | 2.7 | 1.5 |
62 | E00988mRNA_s_at | NM_031511 | Insulin-like growth factor 2 | Igf2 | 3.0 | 1.4 |
63 | U01908cds_s_at///D43778exon#3_s_at///D16840_s_at | NM_012494 | Angiotensin II receptor, type 2 | Agtr2 | 4.4 | 1.4 |
64 | rc_AI176461_s_at | NM_017211 | Golgi apparatus protein 1 | Glg1 | 3.3 | 1.4 |
65 | U23146cds_s_at | NM_057103 | A kinase (PRKA) anchor protein (gravin) 12 | Akap12 | 2.9 | 1.4 |
66 | rc_AA900750_s_at | NM_012760 | Pleiomorphic adenoma gene-like 1 | Plagl1 | 2.5 | 1.4 |
67 | Z17223_at | NM_017149 | Mesenchyme homeo box 2 | Meox2 | 2.6 | 1.3 |
68 | rc_AI171966_at | NM_198740 | Major histocompatibility complex, class II, DM beta | RGD:735096 | 2.5 | 1.2 |
69 | U35775_g_at///U35775_at | NM_031552 | Adducin 3 (gamma) | Add3 | 5.3 | 1.2 |
70 | U43534_at | NM_012894 | Adenosine deaminase, RNA-specific, B1 | Adarb1 | 2.7 | 0.8 |
71 | AF004811_at | NM_030863 | Moesin | Msn | 2.9 | 0.7 |
72 | X05831cds_at///U82612cds_at///M28259cds_at | NM_019143 | Fibronectin 1 | Fn1 | 3.9 | 0.7 |
73 | U17604_at | NM_053865 | Reticulon 1 | Rtn1 | 2.6 | 0.7 |
74 | X51531cds_g_at///X51531cds_at | – | – | – | 4.4 | 30.2 |
75 | rc_AA799865_at | – | Transcribed locus | – | 1.3 | 2.7 |
76 | X05472cds#2_at | – | – | – | 7.2 | 2.4 |
77 | rc_AA799406_at | XM_578859 | Hypothetical protein LOC503325 | LOC503325 | 2.6 | 1.3 |
78 | rc_AA859921_at | – | – | – | 3.3 | 0.9 |