Fig. 1From: Hypothalamic SOCS-3 expression and the effect of intracerebroventricular angiotensin II injection on water intake and renal sodium handling in SHREffect of i.c.v. dose–response injection of AngII on drinking behavior in WKy and SHR rats. Rats were i.c.v. cannulated and received 3.0 μl saline, 3.0 μl of a solution containing AngII or 1 μl DUP753 before 3 μl AngII (amounts stated in the figure). In all groups, the volume of spontaneous water consumption was measured over the next 30 min. In all experiments, n = 5; *P ≤ 0.05 versus saline-treated (ANOVA)Back to article page