Table 1 Permeability ratios (P X/P K) of different cations in Kv1.2 WT and V370G channels
From: Control of ionic selectivity by a pore helix residue in the Kv1.2 channel
Monovalent cations | WT | V370G |
|---|---|---|
Na+ (140 mM Na+, 4 mM K+) | 0.04 ± 0.01 | 0.76 ± 0.12* |
Rb+ (140 mM Rb+, 4 mM K+) | 0.78 ± 0.07 | 1.63 ± 0.33* |
Cs+ (140 mM Cs+, 4 mM K+) | 0.10 ± 0.02 | 1.18 ± 0.29* |
Li+ (140 mM Li+, 4 mM K+) | 0.05 ± 0.01 | 0.13 ± 0.05 |