| Control subjects (n = 9) | TBsq patients (n = 49) |
---|
Before the break point | After the break point | Before the break point | After the break point |
---|
r
| p value |
r
| p value |
r
| p value |
r
| p value |
---|
pH-slope | 0.528 | NS | −0.095 | NS | −0.616 | <0.0001 | −0.629 | <0.0001 |
PaO2-slope | 0.093 | NS | −0.025 | NS | −0.328 | 0.0209 | −0.359 | 0.0108 |
PaCO2-slope | −0.145 | NS | −0.701 | 0.0330 | 0.513 | 0.0001 | 0.583 | <0.0001 |
LT-slope | −0.479 | NS | 0.270 | NS | 0.542 | <0.0001 | 0.498 | 0.0002 |
NE-slope | −0.305 | NS | 0.689 | 0.0393 | 0.443 | 0.0012 | 0.643 | <0.0001 |
HR-slope | −0.090 | NS | −0.177 | NS | 0.363 | 0.0098 | 0.325 | 0.0224 |
f-slope | 0.014 | NS | −0.129 | NS | 0.188 | NS | 0.099 | NS |
VT-slope | 0.059 | NS | 0.088 | NS | −0.160 | NS | −0.142 | NS |
- The exercise-response slopes were calculated when the parameters were plotted against \( \dot{V} {\text{O}}_{ 2} \) from rest to the break point, or from the break point to the peak exercise point using linear regression analysis for each subject
- TBsq, sequelae of pulmonary tuberculosis; \( \dot{V} {\text{O}}_{ 2} \) oxygen uptake; the break point, the dyspnea-\( \dot{V} {\text{O}}_{ 2} \) break point determined by each subject; PaO2, arterial oxygen tension; PaCO2, arterial carbon dioxide tension; LT, plasma lactate level; NE, plasma norepinephrine level
- Dyspnea-slope (∆Borg scale/\( \Updelta \dot{V}_{\text{E}} \)) is expressed as L−1 min, pH-slope (∆pH/\( \Updelta \dot{V} {\text{O}}_{ 2} \)) as L−1 min, PaO2-slope (∆PaO2/\( \Updelta \dot{V} {\text{O}}_{ 2} \)) as mmHg L−1 min, PaCO2-slope (∆PaCO2/\( \Updelta \dot{V} {\text{O}}_{ 2} \)) as mmHg L−1 min, LT-slope (∆LT/\( \Updelta \dot{V} {\text{O}}_{ 2} \)) as mg dL−1 L−1 min, NE-slope (∆NE/\( \Updelta \dot{V} {\text{O}}_{ 2} \)) as ng mL−1 L−1 min, HR-slope (∆Heart rate/\( \Updelta \dot{V} {\text{O}}_{ 2} \)) as beats L−1, f-slope (∆breathing frequency/\( \Updelta \dot{V} {\text{O}}_{ 2} \)) as breaths L−1, V
T-slope (∆tidal volume/\( \Updelta \dot{V} {\text{O}}_{ 2} \)) as mL L−1 min
- NS not significant