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Table 1 The number and IOD of c-Fos-positive neurons in the forebrain in rats under continuous stress (n = 5)

From: c-Fos expression in the supraoptic nucleus is the most intense during different durations of restraint water-immersion stress in the rat

 

Group 0

Group 30

Group 60

Group 120

Group 180

Midline cortical areas

 mPFC

0.95 ± 0.20a

2.36 ± 0.26b

4.01 ± 0.75c

3.50 ± 0.39bc

2.60 ± 0.17b

2.30 ± 0.52a

7.17 ± 0.91ab

17.56 ± 4.03c

12.53 ± 2.43bc

8.72 ± 0.97ab

 Cg

0.90 ± 0.16a

1.55 ± 0.28ab

2.71 ± 0.60c

2.16 ± 0.24bc

1.41 ± 0.10ab

2.56 ± 0.59a

4.50 ± 0.97a

9.37 ± 2.51b

6.35 ± 0.88ab

3.87 ± 0.29a

 RS

0.89 ± 0.20a

1.62 ± 0.31ab

2.36 ± 0.53b

1.37 ± 0.25a

1.23 ± 0.13a

2.06 ± 0.54a

3.48 ± 0.76a

6.83 ± 1.57b

3.25 ± 0.54a

2.83 ± 0.31a

Septal area

 LSv

2.63 ± 0.22a

5.69 ± 0.77b

6.25 ± 0.43b

8.17 ± 0.32c

7.57 ± 0.30c

7.97 ± 0.81a

21.05 ± 4.22b

31.24 ± 3.62c

40.99 ± 4.31c

37.81 ± 1.52c

Amygdala

 CeA

0.71 ± 0.15a

2.18 ± 0.27b

2.80 ± 0.33b

4.96 ± 0.31c

4.35 ± 0.73c

2.70 ± 0.72a

5.94 ± 0.78a

11.36 ± 2.02ab

23.73 ± 2.51c

19.28 ± 4.68bc

 MeA

0.92 ± 0.21a

2.32 ± 0.02b

2.37 ± 0.45b

3.32 ± 0.35c

2.74 ± 0.30bc

3.85 ± 1.06a

9.95 ± 0.77b

13.06 ± 3.03bc

18.65 ± 2.65c

13.49 ± 1.81bc

 PCoA

0.46 ± 0.07a

1.97 ± 0.19b

2.58 ± 0.26bc

3.07 ± 0.47c

2.52 ± 0.14bc

3.02 ± 0.74a

10.40 ± 0.65b

18.00 ± 2.65c

22.01 ± 3.92c

16.25 ± 0.93bc

Hypothalamus

 MPO

1.14 ± 0.24a

2.09 ± 0.25b

1.97 ± 0.50ab

2.87 ± 0.30b

2.08 ± 0.10b

3.27 ± 0.84a

6.86 ± 0.78ab

7.35 ± 2.52ab

10.78 ± 1.27b

6.22 ± 0.47a

 AH

1.51 ± 0.34a

2.62 ± 0.20c

2.39 ± 0.23bc

2.18 ± 0.07bc

1.81 ± 0.14ab

5.32 ± 1.41a

9.92 ± 0.79bc

11.12 ± 1.67c

7.77 ± 0.55ab

5.71 ± 0.29a

 PVN

1.47 ± 0.32a

6.70 ± 0.89b

8.50 ± 0.37b

7.26 ± 1.10b

7.89 ± 0.92b

2.59 ± 0.63a

17.06 ± 1.98b

27.70 ± 2.87b

23.87 ± 4.47b

28.91 ± 5.34b

 SON

0.54 ± 0.10a

4.67 ± 0.87b

7.65 ± 1.43b

7.43 ± 1.47b

5.82 ± 1.05b

1.30 ± 0.29a

18.05 ± 5.17ab

43.60 ± 9.45c

37.82 ± 10.07bc

26.59 ± 7.24bc

 SCh

1.13 ± 0.25a

7.89 ± 0.48c

6.14 ± 1.31bc

8.43 ± 1.01c

4.55 ± 0.62b

3.00 ± 0.78a

22.59 ± 1.63bc

20.54 ± 5.59b

31.90 ± 3.91c

10.70 ± 1.79a

 DMH

2.08 ± 0.47a

3.31 ± 0.34b

3.47 ± 0.42b

4.37 ± 0.40b

3.99 ± 0.14b

6.19 ± 1.66a

13.16 ± 2.58ab

16.98 ± 3.06b

19.91 ± 3.44b

15.19 ± 0.39b

 Arc

1.74 ± 0.43a

3.28 ± 0.37ab

4.02 ± 0.46b

3.84 ± 0.71b

3.71 ± 0.60b

5.22 ± 1.44a

11.73 ± 1.25ab

18.36 ± 2.65b

17.88 ± 3.90b

15.28 ± 3.10b

 SuM

1.84 ± 0.41a

2.96 ± 0.13b

3.47 ± 0.36bc

4.48 ± 0.22c

3.64 ± 0.38bc

6.96 ± 1.78a

13.91 ± 0.94b

20.55 ± 3.11bc

22.04 ± 1.78c

15.98 ± 1.32bc

  1. For each nucleus, the data in the top row represent the number of c-Fos-positive neurons, and the data in the bottom row represent the IOD of c-Fos-positive neurons
  2. Means in a row without a common letter represent significant difference at P < 0.05
  3. AH Anterior hypothalamic area, Arc arcuate hypothalamic nucleus, CeA central amygdaloid nucleus, Cg cingulated cortex, DMH dorsomedial hypothalamic nucleus, LSv ventrolateral septum, MeA medial amygdaloid nucleus, mPFC medial prefrontal cortex, MPO medial preoptic nucleus, PCoA posterior cortical amygdaloid nucleus, PVN hypothalamic paraventricular nucleus, RS retrosplenial cortex, SCh suprachiasmatic nucleus, SON supraoptic nucleus, SuM supramammillary nucleus