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  1. Distress vocalizations are fundamental for survival, and both sonic and ultrasonic components of such vocalizations are preserved phylogenetically among many mammals. On this basis, we hypothesized that ultras...

    Authors: Hirokazu Doi, Simone Sulpizio, Gianluca Esposito, Masahiro Katou, Emi Nishina, Mayuko Iriguchi, Manabu Honda, Tsutomu Oohashi, Marc H. Bornstein and Kazuyuki Shinohara

    Citation: The Journal of Physiological Sciences 2019 69:729

    Content type: Original Paper

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  2. Menopause is a risk factor for impaired glucose metabolism. Alternative treatment of estrogen for postmenopausal women is required. The present study was designed to investigate the effects of 5-week endurance...

    Authors: Mizuho Kawakami, Naoko Yokota-Nakagi, Akira Takamata and Keiko Morimoto

    Citation: The Journal of Physiological Sciences 2019 69:723

    Content type: Original Paper

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  3. Hypoglycemia-associated autonomic failure (HAAF) is a serious complication of diabetes which is associated with the absence of physiological homeostatic counter-regulatory mechanisms that are controlled by the...

    Authors: Bashair M. Mussa, Jalal Taneera, Abdul Khader Mohammed, Ankita Srivastava, Debasmita Mukhopadhyay and Nabil Sulaiman

    Citation: The Journal of Physiological Sciences 2019 69:718

    Content type: Original Paper

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  4. An atrial tachyarrhythmias is predominantly triggered by a proarrhythmic activity originate from the pulmonary veins (PV) myocardial sleeves; sympathetic or adrenergic stimulation facilitates PV proarrhythmia....

    Authors: V. M. Potekhina, O. A. Averina, A. A. Razumov, V. S. Kuzmin and L. V. Rozenshtraukh

    Citation: The Journal of Physiological Sciences 2019 69:724

    Content type: Original Paper

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  5. When choosing the best action from several alternatives, we compare each value that depends on the balance between benefit and cost. Previous studies have shown that animals and humans with low brain serotonin...

    Authors: Fumika Akizawa, Takashi Mizuhiki, Tsuyoshi Setogawa, Mai Takafuji and Munetaka Shidara

    Citation: The Journal of Physiological Sciences 2019 69:725

    Content type: Original Paper

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  6. Increasing evidence demonstrates that electric stimulation has anticonvulsant effects. The present study was undertaken to investigate the effects of mild foot electrical stimulation (MFES) on the development ...

    Authors: Arefe Ghasemi-Dehno, Abolfazl Jand, Monir Abasi-Moghadam, Mehdi Sadegh, Morteza Mousavi-Hasanzadeh and Mohammad Reza Palizvan

    Citation: The Journal of Physiological Sciences 2019 69:726

    Content type: Original Paper

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  7. Mesenchymal stem cells (MSCs) are regarded as unique cells which play an imperative role in the field of regenerative medicine. They are characterized by the self-renewal capacity, multi-lineage differentiatio...

    Authors: Ramada R. Khasawneh, Ejlal Abu-El-Rub, Abdullah Omar Serhan, Bashar Omar Serhan and Hadeel Abu-El-Rub

    Citation: The Journal of Physiological Sciences 2019 69:720

    Content type: Original Paper

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  8. To investigate the exercise intensity effects on rats’ memory and learning, animals were divided into control, moderate training (MT), and overtraining (OT) groups. At training last week, learning and memory w...

    Authors: Zahra Jahangiri, Zahra Gholamnezhad, Mahmoud Hosseini, Farimah Beheshti and Narges Kasraie

    Citation: The Journal of Physiological Sciences 2019 69:719

    Content type: Original Paper

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  9. The aim of this study was to investigate the effect of activated ghrelin with dietary octanoic acids or medium-chain triglyceride (MCT) administration to underweight patient with chronic obstructive pulmonary ...

    Authors: Keisuke Miki, Seigo Kitada, Mari Miki, Shu-Ping Hui, Rojeet Shrestha, Kenji Yoshimura, Kazuyuki Tsujino, Hiroyuki Kagawa, Yohei Oshitani, Hiroshi Kida, Ryoji Maekura and Kenji Kangawa

    Citation: The Journal of Physiological Sciences 2019 69:716

    Content type: Original Paper

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  10. Milk supply and quality during lactation are critical for progeny survival. Maternal tissues and metabolism, influenced by hormonal changes, undergo modification during lactation to sustain breastfeeding. Two ...

    Authors: Gustavo Canul-Medina and Cristina Fernandez-Mejia

    Citation: The Journal of Physiological Sciences 2019 69:714

    Content type: Review

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  11. In the diabetic brain, hyperglycemia damages the cerebrovasculature and impairs neurovascular crosstalk. Calcitonin gene-related peptide (CGRP) is an important neuropeptide that is active in the vascular syste...

    Authors: Yanjun Guo, Qin Zhang, Huilu Chen, Yixuan Jiang and Ping Gong

    Citation: The Journal of Physiological Sciences 2019 69:708

    Content type: Original Paper

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  12. Motor units are generally recruited from the smallest to the largest following the size principle, while cutaneous stimulation has the potential to affect spinal motor control. We aimed to examine the effects ...

    Authors: Kotaro Tamura, Satoshi Sugita, Tadayuki Tokunaga, Yoshihiko Minegishi and Noriyasu Ota

    Citation: The Journal of Physiological Sciences 2019 69:707

    Content type: Original Paper

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  13. The vestibular system contributes to not only eye movement and posture but also the sympathetic response. Plastic alteration of the vestibulo-sympathetic reflex is induced by hypergravity load; however, the me...

    Authors: Chikara Abe, Yusuke Yamaoka, Yui Maejima, Tomoe Mikami and Hironobu Morita

    Citation: The Journal of Physiological Sciences 2019 69:705

    Content type: Original Paper

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  14. Exercise has an effect on the reduction of myocardial fibrosis in diabetic rats as previously reported, in which oxidative stress and the TGF-β1/Smad signaling pathway may play key roles. There is little direc...

    Authors: Shi-Qiang Wang, Dan Li and Yang Yuan

    Citation: The Journal of Physiological Sciences 2019 69:696

    Content type: Original Paper

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  15. We investigated the effect of muscle damage and inflammation on electrical resistance and the body composition assessment by using bioimpedance spectroscopy (BIS). Twenty-two subjects completed 30 repetitions ...

    Authors: Keisuke Shiose, Yoko Tanabe, Takahiro Ohnishi and Hideyuki Takahashi

    Citation: The Journal of Physiological Sciences 2019 69:702

    Content type: Original Paper

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  16. Intermittent claudication (IC) is the most common symptom of peripheral arterial disease which significantly deteriorates the quality of life of patients. Exercise training is by far the most effective treatme...

    Authors: Momoko Shiragaki-Ogitani, Keita Kono, Futoshi Nara and Atsushi Aoyagi

    Citation: The Journal of Physiological Sciences 2019 69:701

    Content type: Original Paper

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  17. In congestive heart failure (CHF), while resting parasympathetic activity becomes reduced, parasympathetically-mediated responses to stressors have not been described. This study aimed to (1) elucidate the eff...

    Authors: Satoshi Koba, Ichiro Hisatome and Tatsuo Watanabe

    Citation: The Journal of Physiological Sciences 2019 69:698

    Content type: Original Paper

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  18. Near-infrared spectroscopy (NIRS) has become an increasingly valuable tool to monitor tissue oxygenation (Toxy) in vivo. Observations of changes in the absorption of light with Toxy have been recognized as early ...

    Authors: Takafumi Hamaoka and Kevin K. McCully

    Citation: The Journal of Physiological Sciences 2019 69:697

    Content type: Review

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  19. Serum testosterone concentration decreases with age in humans and rodents. Accordingly, old male mice show changes in locomotor activity rhythms: a lengthened free-running period and decreased activity levels ...

    Authors: Atsuyoshi Hashimoto, Shingo Fujiki, Wataru Nakamura and Takahiro J. Nakamura

    Citation: The Journal of Physiological Sciences 2019 69:695

    Content type: Original Paper

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  20. Intermittent hyperbaric oxygen exposure (IE-HBO) can protect the body against oxygen toxicity, but the underlying mechanisms are not very clear. Peroxiredoxin 6 (Prdx6) is a special endogenous antioxidative pr...

    Authors: Lichao Zhang, Yanan Zhang, Zhongzhuang Wang, Yuliang Chen and Runping Li

    Citation: The Journal of Physiological Sciences 2019 69:694

    Content type: Original Paper

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  21. The effects of a combination of the antioxidant astaxanthin (AX) and electrical stimulation (ES) on muscle mass and mitochondrial oxidative capacity were investigated in the soleus muscle of hindlimb unloaded ...

    Authors: Miho Kanazashi, Masayuki Tanaka, Ryosuke Nakanishi, Noriaki Maeshige and Hidemi Fujino

    Citation: The Journal of Physiological Sciences 2019 69:692

    Content type: Original Paper

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  22. The effects of the pharyngeal non-noxious mechanical stimulation on the secretion of immunoreactive thyroxin (iT4), immunoreactive calcitonin (iCT), and immunoreactive parathyroid hormone (iPTH) into thyroid v...

    Authors: Kaori Iimura, Harue Suzuki and Harumi Hotta

    Citation: The Journal of Physiological Sciences 2019 69:691

    Content type: Original Paper

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  23. Operant methods that allow animals to avoid painful stimuli are interpreted to assess the aversive quality of pain; however, such measurements require investigator-initiated stimuli to animals. Here we develop...

    Authors: Ken-ichiro Hayashida, James C. Eisenach, Masahito Kawatani and Thomas J. Martin

    Citation: The Journal of Physiological Sciences 2019 69:693

    Content type: Original Paper

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  24. We have previously reported that increased extracellular and intracellular Ca2+ lead to adipocyte accumulation in bone marrow stromal cells (BMSCs). However, strategies to suppress high Ca2+-enhanced adipocyte ac...

    Authors: Ryota Hashimoto, Yuki Miyamoto, Seigo Itoh, Hiroyuki Daida, Takao Okada and Youichi Katoh

    Citation: The Journal of Physiological Sciences 2019 69:690

    Content type: Original Paper

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  25. Nesfatin-1 is a hypothalamic anorexigenic peptide processed from nucleobindin 2 (NUCB2). Central and peripheral administration of NUCB2/nesfatin-1 enhances glucose metabolism and insulin release. NUCB2/nesfati...

    Authors: Yifei Yang, Boyang Zhang, Masanori Nakata, Jun Nakae, Masatomo Mori and Toshihiko Yada

    Citation: The Journal of Physiological Sciences 2019 69:689

    Content type: Original Paper

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  26. Besides the two canonical calciotropic hormones, namely parathyroid hormone and 1,25-dihydroxyvitamin D [1,25(OH)2D3], there are several other endocrine and paracrine factors, such as prolactin, estrogen, and ins...

    Authors: Kannikar Wongdee, Mayuree Rodrat, Jarinthorn Teerapornpuntakit, Nateetip Krishnamra and Narattaphol Charoenphandhu

    Citation: The Journal of Physiological Sciences 2019 69:688

    Content type: Review

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  27. Our previous demonstration that severe experimental autoimmune encephalomyelitis (EAE) increases MnSOD protein abundance in the mouse kidney cortex led this study to elucidate the underlying mechanism with mon...

    Authors: Sharanpreet Hira, Balamuguran Packialakshmi and Xiaoming Zhou

    Citation: The Journal of Physiological Sciences 2019 69:687

    Content type: Original Paper

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  28. Endoplasmic reticulum (ER) stress is involved in inflammation-induced neurotoxicity. Mitofusin 2 (Mfn2), a member of the GTPase family of proteins, resides in the ER membrane and is known to regulate ER stress...

    Authors: Shu Hou, Lili Wang and Guoping Zhang

    Citation: The Journal of Physiological Sciences 2019 69:685

    Content type: Original Paper

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  29. A high-fat diet (HFD) and overweight status can induce hippocampal dysfunction, leading to depression and anxiety. Exercise has beneficial effects on emotional behaviors. We previously reported that exercise t...

    Authors: Yuki Tomiga, Saki Yoshimura, Song-Gyu Ra, Yuri Takahashi, Rina Goto, Ikumi Kugimoto, Yoshinari Uehara, Kentaro Kawanaka and Yasuki Higaki

    Citation: The Journal of Physiological Sciences 2019 69:686

    Content type: Original Paper

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  30. Sodium-coupled monocarboxylate transporter SMCT1 (SLC5A8) mediates monocarboxylate transport in the proximal tubule of the kidney. We have identified PDZK1 and PDZ domain-containing RING finger 3 (PDZRN3) as p...

    Authors: Yusuke Otsuka, Tomomi Furihata, Kiyoshi Nakagawa, Yuta Ohno, Yoshie Reien, Motoshi Ouchi, Hidefumi Wakashin, Shuichi Tsuruoka and Naohiko Anzai

    Citation: The Journal of Physiological Sciences 2019 69:681

    Content type: Original Paper

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  31. Hypokalemia, an abnormally low level of potassium (K+), is a electrolyte imbalance that commonly occurs in heart failure patients. Hypokalemia is well known to induce lethal ventricular arrhythmia. However, the e...

    Authors: Kensuke Oshita, Yuko Kozasa, Yasuaki Nakagawa, Yoshihiro Kuwabara, Koichiro Kuwahara, Taku Nakagawa, Noriyuki Nakashima, Teruyuki Hiraki and Makoto Takano

    Citation: The Journal of Physiological Sciences 2019 69:684

    Content type: Original Paper

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  32. Silibinin has been shown to attenuate cognitive dysfunction and inhibit amyloid-beta (Aβ) aggregation in Alzheimer’s disease (AD) models. However, the underlying mechanism by which silibinin improves cognition...

    Authors: Dafeng Bai, Ge Jin, Dajun Zhang, Lini Zhao, Mingyue Wang, Qiwen Zhu, Lin Zhu, Yan Sun, Xuan Liu, Xueying Chen, Liqian Zhang, Wenbo Li and Yan Cui

    Citation: The Journal of Physiological Sciences 2019 69:682

    Content type: Original Paper

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  33. Duchenne muscular dystrophy is a severe muscular disorder, often complicated with osteoporosis, and impaired renal function has recently been featured. We aimed to clarify the involvement of renal function in ...

    Authors: Eiji Wada, Takayuki Hamano, Isao Matsui, Mizuko Yoshida, Yukiko K. Hayashi and Ryoichi Matsuda

    Citation: The Journal of Physiological Sciences 2019 69:683

    Content type: Original Paper

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  34. Japanese menopausal women who feel cold, even in a warm room, are said to be experiencing “hie-sho.” We assessed the magnitude of coldness by a “hie-sho” interview score. The association between the magnitude ...

    Authors: Yuki Uchida, Kyoko Ueshima, Koko Kano, Mayuko Minami, Yuri Mizukami and Keiko Morimoto

    Citation: The Journal of Physiological Sciences 2019 69:680

    Content type: Short Communication

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  35. Adequate oxygen supply by exposure to mild hyperbaric oxygen at appropriately high atmospheric pressure (1266–1317 hPa) and increased oxygen concentration (35–40% oxygen) has a possibility of improving the oxi...

    Authors: Akihiko Ishihara

    Citation: The Journal of Physiological Sciences 2019 69:678

    Content type: Review

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  36. Appropriate cardiovascular adjustment is necessary to meet the metabolic demands of working skeletal muscle during exercise. The sympathetic nervous system plays a crucial role in the regulation of arterial bl...

    Authors: Keisho Katayama and Mitsuru Saito

    Citation: The Journal of Physiological Sciences 2019 69:669

    Content type: Mini-review

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  37. TRPM3 is a non-selective cation channel that is activated by neural steroids such as pregnenolone sulfate, nifedipine, and clotrimazole. Despite the number of TRPM3 variants, few reports have described functio...

    Authors: Kunitoshi Uchida, Naomi Fukuta, Jun Yamazaki and Makoto Tominaga

    Citation: The Journal of Physiological Sciences 2019 69:677

    Content type: Original Paper

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  38. Water intake is recommended for weight loss, but the relationship between water intake and energy metabolism is not clear. We hypothesized that long-term water insufficiency would influence energy, glucose, an...

    Authors: James W. Daily, Ting Zhang, Xuangao Wu and Sunmin Park

    Citation: The Journal of Physiological Sciences 2019 69:668

    Content type: Original Paper

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  39. The aim of this study was to investigate how odor stimulation affects taste perception. Electroencephalogram (EEG) signals were measured from the frontal region of the head in normal, healthy subjects, and fre...

    Authors: Saori Maeda and Hiroshi Yoshimura

    Citation: The Journal of Physiological Sciences 2019 69:674

    Content type: Original Paper

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  40. Periodontitis, which is caused by various oral organisms, predominantly affects adults, and is one of the main causes of tooth loss, as well as leading to progression of numerous systemic diseases. However, it...

    Authors: Naoya Kawamura, Yoshiki Ohnuki, Ichiro Matsuo, Kenji Suita, Misao Ishikawa, Yasumasa Mototani, Kouichi Shiozawa, Aiko Ito, Yuka Yagisawa, Yoshio Hayakawa, Megumi Nariyama, Daisuke Umeki, Yuko Ujiie, Kazuhiro Gomi and Satoshi Okumura

    Citation: The Journal of Physiological Sciences 2019 69:670

    Content type: Original Paper

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  41. The article Inhibition of ghrelin-induced feeding in rats by pretreatment with a novel dual orexin receptor antagonist, written by Mariko So, Hirofumi Hashimoto

    Authors: Mariko So, Hirofumi Hashimoto, Reiko Saito, Yukiyo Yamamoto, Yasuhito Motojima, Hiromichi Ueno, Satomi Sonoda, Mitsuhiro Yoshimura, Takashi Maruyama, Koichi Kusuhara and Yoichi Ueta

    Citation: The Journal of Physiological Sciences 2019 69:665

    Content type: Correction

    Published on:

    The original article was published in The Journal of Physiological Sciences 2017 68:s12576-016-0517-5

  42. The article Epac activation inhibits IL-6-induced cardiac myocyte dysfunction.

    Authors: Huiling Jin, Takayuki Fujita, Meihua Jin, Reiko Kurotani, Yuko Hidaka, Wenqian Cai, Kenji Suita, Rajesh Prajapati, Chen Liang, Yoshiki Ohnuki, Yasumasa Mototani, Masanari Umemura, Utako Yokoyama, Motohiko Sato, Satoshi Okumura and Yoshihiro Ishikawa

    Citation: The Journal of Physiological Sciences 2019 69:661

    Content type: Correction

    Published on:

    The original article was published in The Journal of Physiological Sciences 2016 68:s12576-016-0509-5

  43. We have developed a concave-shaped transparent electrode unit that enables the placement of several electrodes within the optical sampling area on the spherical surface of the rat brain. This concave-shaped tr...

    Authors: Noriyuki Hama, Minako Kawai, Shin-ichi Ito, Yuki Yoshida, Yasuhisa Fujita and Akihiko Hirota

    Citation: The Journal of Physiological Sciences 2019 69:663

    Content type: Technical Note

    Published on:

  44. The article Hypotonicity-induced cell swelling activates TRPA1, written by Fumitaka Fujita, Kunitoshi Uchida, Yasunori Takayama, Yoshiro Suzuki, Masayuki Takaishi and Makoto Tominaga, was originally published ...

    Authors: Fumitaka Fujita, Kunitoshi Uchida, Yasunori Takayama, Yoshiro Suzuki, Masayuki Takaishi and Makoto Tominaga

    Citation: The Journal of Physiological Sciences 2019 69:662

    Content type: Correction

    Published on:

    The original article was published in The Journal of Physiological Sciences 2017 68:s12576-017-0545-9

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