Fig. 2

Effects of treatment on heart rate (HR) and mean blood pressure (MBP) of rats with RMI-induced CHF, recorded using telemetry. a Weekly HR. Each point represents averaged 1-week data for all animals in each group. b Daily average HR during week 1. Each point represents the averaged 1-day data for all animals in each group. (UT, n = 14; DT, n = 16; MT, n = 18; DMT, n = 14). c Weekly MBP. Each point represents averaged 1-week data for all animals in each group. Values are expressed as means ± SEMs. a–d P < 0.05; aa, bb, cc and dd P < 0.01 vs. pretreatment value (week 0, day 0, at 1-h post-RMI) within each group (UT, DT, MT or DMT); *P < 0.05, **P < 0.05 vs. UT groups, using one-way ANOVA and post-hoc Dunnett’s test. CHF, chronic heart failure