Fig. 5

Hsa_circ_0000345 repressed cell proliferation, migration and invasion of SUNE1 cells by promoting PTEN. SUNE1 cells were co-transfected with pcDNA3.1-hsa_circ_0000345 or pcDNA3.1-NC and Si-PTEN or Si-NC. A MTT assay was performed to examine cell proliferation of the transfected SUNE1 cells. B, C Transwell assay was performed to estimate cell migration and invasion of the transfected SUNE1 cells. **P < 0.01 vs. Vector + Si-NC; ^##P < 0.01 vs. Vector + Si-PTEN