Fig. 6
From: Bicarbonate transport of airway surface epithelia in luminally perfused mice bronchioles
Effects of luminal amiloride on pHi in bronchiole epithelial cells. a–f Isolated bronchioles were first bilaterally perfused with the standard Hepes-buffered HCO3−–CO2-free solution (a, c, e) or the standard HCO3−-buffered solution (b, d, f). Amiloride was applied to the lumen as indicated at concentrations of 1 μM (a, b), 10 μM (c, d) or 100 μM (e, f). Time course changes of pHi are shown as means ± SD of 8 experiments. g Increase or decrease of pHi (ΔpH for 5 min) by luminal application of amiloride at various concentrations