Fig. 5From: MiR-18a-3p improves cartilage matrix remodeling and inhibits inflammation in osteoarthritis by suppressing PDP1As shown in the diagram, IL-1β downregulates miR-18a-3p in ATDC5 cells. miR-18a-3p directly targets PDP1, and PDP1 promotes the concentration of inflammatory cytokines and matrix metalloproteinase. Thus, miR-18a-3p suppresses levels of inflammatory cytokines and matrix metalloproteinase by targeting PDP1 in IL-1β-stimulated ATDC5 cellsBack to article page