Fig. 3
From: Vidarabine, an anti-herpes agent, prevents occlusal-disharmony-induced cardiac dysfunction in mice
Effect of vidarabine on BO-induced cardiac myocyte apoptosis. a TUNEL-positive nuclei (black arrows) in representative TUNEL-stained sections were counted in cardiac muscle in the Control (CTRL; upper left), BO (upper right), Vidarabine (V; lower left) and BO + V (lower right) groups. b The number of TUNEL-positive nuclei was significantly increased in the BO group (n = 5), but this increase was blocked in the BO + V group (n = 4). *P < 0.05 by one-way ANOVA followed by the Tukey–Kramer post hoc test. c The Bax/BCL-2 ratio was significantly increased in the BO group (n = 4), but this increase was blocked in the BO + V group (n = 5). *P < 0.05 by one-way ANOVA followed by the Tukey–Kramer post hoc test. Data are presented as mean ± SD. Full-size images of immunoblots are presented in Additional file 1: Fig. S4