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Fig. 2 | The Journal of Physiological Sciences

Fig. 2

From: miR-153/KCNQ4 axis contributes to noise-induced hearing loss in a mouse model

Fig. 2

Noise-induced TTS and PTS in adult CBA/J mice. A TTS: 96 dB SPL induced significant threshold shifts at 8, 16, and 32 kHz 3 h after exposure with complete recovery by day 3. n = 10 at each time. B PTS: 101 dB SPL induced significant threshold shifts at 8, 16, and 32 kHz 1 days after noise exposure that are maintained through 14 days. n = 10 at each time. C Quantification of OHC losses 7 days after noise exposure revealed more OHC loss with PTS compared to TTS. n = 10 for each group. D Quantification of IHC losses 7 days after noise exposure revealed no IHC loss in both groups. n = 10 for each group. Data were presented as mean ± SD. ***P < 0.001 compared to TTS. Two-way ANOVA followed Tukey's multiple comparisons test

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