Fig. 6

Time-dependent changes in hippocampal responses to perforant path stimulation following HFS. LTP of the PS amplitude in area DG granular cell synapses of the hippocampus are significantly different between groups. Left panel shows PS amplitude change (%) vs. time following HFS in different experimental groups. Bar graphs show the average PS amplitude change (%) during 60 min post-HFS. Data are expressed as means ± SEM % of baseline. *P < 0.05, ***P < 0.001