Fig. 1

Experimental design and timeline. Animals were maintained on HFD or standard diet regimes as per the protocol for 90 days before subjecting them for electrophysiological recording. The extract (1 g/kg bw daily) was administered by oral gavage for 30 days. After that, once a stable baseline was observed for at least 40 min, LTP was induced by applying HFS consisting of 10 bursts of 20 stimuli, 0.2 ms stimulus duration, 10 s interburst interval in the DG of rats. HFS; high-frequency stimulation